Impacto del consumo de cannabis y base de cocaÃna sobre la memoria
Abstract
Resumen
Diversos estudios han confirmado que la drogodependencia al cannabis y a la cocaÃna genera alteraciones en la cognición debido a la modificación neurobiológica y quÃmica cerebral. Objetivo: Comparar los resultados de la memoria asociados al consumo dependiente de cannabis y base de cocaÃna entre un grupo clÃnico y un grupo control. Método: Estudio transversal, exploratorio, descriptivo, comparativo y estadÃstico, donde participaron 80 individuos de ambos sexos, de entre 20 y 40 años de edad y con 6 a 18 años de escolaridad. Divididos en dos grupos de 40 sujetos cada uno. La muestra clÃnica, fue reclutada mediante los resultados de un panel de drogas para determinar el tipo y grado de toxicidad en el organismo. Ambos grupos fueron evaluados con el Neuropsi. Resultados: El grupo clÃnico en relación al control puntúa más bajo en la memoria sensorial, memoria a corto plazo, memoria de trabajo, con afectación de la curva de aprendizaje, fallos en la integración de información semántica. Conclusiones: Se encontraron diferencias significativas de la memoria entre los grupos, excepto en la codificación.
Palabras clave: memoria; drogodependencia; cannabis; base de cocaÃna; drogas; ArtÃculo Original; Reporte de Investigación
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Abstract
Justification: Several studies have confirmed that cannabis and cocaine addiction generates cognition alterations due to neurobiological and chemical modification of the brain. Aim: To compare results of memory related to dependent consumption of cannabis and cocaine base in a clinical group and in a control group. Methodology: cross-sectional, exploratory, descriptive and comparative study, where 80 individuals from both sexes participated, ages 20 to 40 and with 6 to 18 years of education, divided into two groups of 40. The clinic sample was selected through the results of a drug panel to determine the type and degree of toxicity in the body. Both groups were evaluated with Neuropsi. Results: The clinic group, in relation with the control group, rank lower in sensory memory, short term memory and working memory with a detriment in the learning curve, fail to integrate semantic information. Conclusions: Important differences in memory between both groups were found, except for codification
Key words:Â memory, drug addiction, cannabis, cocaine base, drugs; investigation report
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